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| Title | Authors | Journal | Year | Vol | Pages |
|---|---|---|---|---|---|
| Novobiocin primarily targets ParE in Neisseria gonorrhoeae. | Y. Ishizaki, C. Hayashi, K. Matoba, and M. Igarashi | J. Antibiot. | 2024 | https://doi.org/10.1038/s41429-024-00797-1 | |
| Structural view on autophagosome formation. | N. N. Noda | FEBS Letters | 2024 | 598 | 84-106, doi:10.1002/1873-3468.14742 |
| The UFM1 system: working principles cellular functions, and pathophysiology. | M. Komatsu, T. Inada, and N. N. Noda | Molecular Cell | 2024 | 84 | https://doi.org/10.1016/j.molcel.2023.11.034 |
| In2Q2: a new entry of 16-membered tetraazamacrocycle concatenating indole and quinoline units. | K. Kihara, T. Kobayashi, W. Xu, and N. Kumagai | Chem. Eur. J | 2024 | 30 | doi.org/10.1002/chem.202304176 |
| Protein phosphatase 2A inhibitor modulates natural killer cell homeostasis in peripheral tissues. | Y. Shinzawa, S. Sasaki, S. Iwabuchi, S. Hashimoto, M. Kawada, and Y. Hayakawa | Biochemical and Biophysical Research Communications | 2024 | 741 | 151020, https://doi.org/10.1016/j.bbrc.2024.151020 |
| A cancer-specific anti-podoplanin monoclonal antibody, PMab-117-mG2a exerts antitumor activities in human tumor xenograft models. | T. Tanaka, H. Suzuki, T. Ohishi, M. K. Kaneko, and Y. Kato | Cells | 2024 | 13 | 1833, https://doi.org/10.3390/cells13221833 |
| PP2A negatively regulates NK cell T-bet expression and anti-tumor effector function. | Y. Shinzawa, D. Hara, Y. Shinguryo, S. Yokoyama, M. Kawada, and Y. Hayakawa | Int Immunol. | 2024 | doi: 10.1093/intimm/dxae057. | |
| Thiazoplanomicin, a new thiazolyl peptide antibiotic from the leaf-litter actinomycete Actinoplanes sp. MM794L-181F6. | Y. Takehana, H. Muramatsu, M. Hatano, Y. Ishizaki, M. Umekita, Y.Shibuya, C. Hayashi, T. Kimura, T. Takeuchi, K. Shimuta, R. Sawa, and M. Igarashi | J. Antibiot. | 2024 | doi: 10.1038/s41429-024-00783-7. | |
| Spencermartinsiella japonica f.a., sp. nov., a novel yeast species isolated from biofilm in a reverse osmosis system. | H. Doi, A. Mishima, and R. Ikeda | Mycoscience | 2024 | 65 | 224-227, doi: 10.47371/mycosci.2024.05.004 |
| Hepatocyte Period 1 dictates oxidative substrate selection independent of the core circadian clock. | J. Sun, Y. Zhang, J. Adams, C. Higgins, S. Kelly, H. Zhang, K. Cho, U. Johnson, B. Swarts, S. Wada, G. Patti, L. Shriver, B. Finck, E. Herzog, and B. DeBosch | Cell Reports | 2024 | 43 | https://www.cell.com/cell-reports/fulltext/S2211-1247(24)01216-6 |
| Pyricularia oryzae enhances Streptomyces griseus growth via non-volatile alkaline metabolites. | R. Sugita, T. Arazoe, T. Motoyama, H. Osada, T. Kamakura, K. Kuramochi, and Y. Furuyama | Environmental Microbiology Reports | 2024 | 16 | e70012. https://doi.org/10.1111/1758-2229.70012 |
| Direct catalytic asymmetric conjugate addition of benzofuran-3(2H)-ones to α,β-unsaturated thioamides: stereodivergent synthesis of rocaglaol. | S. Samanta, H. Noda, T. Watanabe, J. Cui, and M. Shibasaki | Angewandte Chemie International Edition | 2024 | e202415805. doi: 10.1002/anie.202415805. | |
| Enhanced anticancer activity of 7MeERT over Ertredin: a comparative study on cancer cell proliferation and NDUFA12 binding. | S. Atsumi, C. Nosaka, T. Onodera, H. Adachi, T. Watanabe, M. Kawada, M. Shibuya, S. I. Park, and H. J. Kwon | Biomolecules | 2024 | 14 | 1197. https://doi.org/10.3390/biom14091197 |
| Antitumor activities of anti‑CD44 monoclonal antibodies in mouse xenograft models of esophageal cancer. | K. Ishikawa, H. Suzuki, T. Ohishi, T. Nakamura, M. Yanaka, G. Li, T. Tanaka, A. Ohkoshi, M. Kawada, M. K. Kaneko, Y. Katori, and Y. Kato | Oncol Rep. | 2024 | 52 | 147. doi: 10.3892/or.2024.8806. |
| Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. | J. Tomono, K. Asano, T. Chiashi, M. Suzuki, M. Igarashi, Y. Takahashi, Y. Tanaka, and T. Yokoyama | J. Biochem. | 2024 | 175 | 587-598. doi: 10.1093/jb/mvae002. |
| Antiproliferative activities through accelerating autophagic flux by basidalin and its analogs in human cancer cells. | T. Matagawa, Y. Sasazawa, K. Agui, M. Fujimaki, S. Kawano, A. Ogura, KI. Takao, M. Igarashi, and S. Simizu | Bioorg Med Chem Lett. | 2024 | 104 | 129713. doi: 10.1016/j.bmcl.2024.129713. |
| Synthesis and biochemical characterization of naphthoquinone derivatives targeting bacterial histidine kinases. | T. Ishikawa, Y. Eguchi, M. Igarashi, T. Okajima, K. Mita, Y. Yamasaki, K. Sumikura, T. Okumura, Y. Tabuchi, C. Hayashi, M. Pasqua, M. Coluccia, G. Prosseda, B. Colonna, C. Kohayakawa, A. Tani, JI. Haruta, and R. Utsumi |
J. Antibiot. | 2024 | 77 | 522–532, https://doi.org/10.1038/s41429-024-00726-2 |
| Impaired glycosylation of gastric mucins drives gastric tumorigenesis and serves as a novel therapeutic target. | J. Arai, Y. Hayakawa, H. Tateno, K. Murakami, T. Hayashi, M. Hata, Y. Matsushita, H. Kinoshita, S. Abe, K. Kurokawa, Y. Oya, M. Tsuboi, S. Ihara, R. Niikura, N. Suzuki, Y. Iwata, T. Shiokawa, C. Shiomi, C. Uekura, K. Yamamoto, H. Fujiwara, S. Kawamura, H. Nakagawa, S. Mizuno, T. Kudo, S. Takahashi, T. Ushiku, Y. Hirata, C. Fujii, J. Nakayama, S. Shibata, S. Woods, D. L. Worthley, M. Hatakeyama, T. C. Wang, and M. Fujishiro | Gastroenterology | 2024 | 167 | 505-521, doi: 10.1053/j.gastro.2024.03.037. |
| Quality evaluation of gentamicin sulfate reference standards in Japanese Pharmacopoeia using hydrophilic Interaction chromatography combined with tandem mass spectrometry. | K. Maekawa, R. Sawa, M. Matsui, T. Konda, Y. Kubota, A. Matsuo, A. Maeda, C. Takahashi, T. Tanimoto, Y. Nakagawa, S. Yoneda, Y. Mori, and S. Suzuki | J AOAC Int. | 2024 | 107 | 234-241. doi: 10.1093/jaoacint/qsad135. |
| Copper-catalyzed direct asymmetric aldol reaction of glycine Schiff bases to access syn-β-hydroxy-α-amino esters. | T. Takeuchi and M. Shibasaki | Org. Lett. | 2024 | 26 | 7981-7986. https://doi.org/10.1021/acs.orglett.4c03085 |
| Catalytic asymmetric Mannich-type reaction of α‑haloacetonitriles. | A. Saito and M. Shibasaki | Org. Lett. | 2024 | 26 | 7546-7550. https://doi.org/10.1021/acs.orglett.4c02505 |
| An immune-adrenergic pathway induces lethal levels of platelet-activating factor in mice. | S. Tanaka, M. Kawakita, H. Yasui, K. Sudo, F. Itoh, M. Sasaki, N. Shibata, H. Hara, Y. Iwakura, T. Hashidate-Yoshida, H. Shindou, T. Shimizu, T. Oyama, H. Matsunaga, and K. Takahara | Communications Biology | 2024 | 7 | 782, https://doi.org/10.1038/s42003-024-06498-7 |
| The role of lysophosphatidylcholine acyltransferase 2 in osteoblastic differentiation of C2C12 cells. | S. Tabe, H. Hikiji, T. Hashidate-Yoshida, H. Shindou, T. Shimizu, and K. Tominaga | FEBS Open Bio | 2024 | 14 | 1490-1502, doi:10.1002/2211-5463.13845 |
| Hepatocyte MMP14 mediates liver and inter-organ inflammatory responses to diet-induced liver injury. | S. Kelly, C. Higgins, J. Sun, J. Adams, Y. Zhang, S. Ballentine, Y. Miao, X. Cui, M. Milewska, I. Wandzik, J. Yoshino, B. Swarts, S. Wada, and B. DeBosch | PNAS Nexus | 2024 | 3 | 357, https://doi.org/10.1093/pnasnexus/pgae357 |
| Anti-CD44 variant 10 monoclonal antibody exerts antitumor activity in mouse xenograft models of oral squamous cell carcinomas. | K. Ishikawa, H. Suzuki, T. Ohishi, G. Li, T. Tanaka, M. Kawada, A. Ohkoshi, M. K. Kaneko, and Y. Kato | Int. J. Mol. Sci. | 2024 | 25 | 9190, https://doi.org/10.3390/ijms25179190 |
| Anti-HER2 cancer-specific mAb, H2Mab-250-hG1, possesses higher complement-dependent cytotoxicity than trastuzumab. | H. Suzuki, T. Ohishi, T. Tanaka, M. K. Kaneko, and Y. Kato | Int. J. Mol. Sci. | 2024 | 25 | 8386, https://doi.org/10.3390/ijms25158386 |
| Visualization of phospholipid synthesis on tissue sections using functional mass spectrometry imaging. | T. Iwama, K. Kano, H. Kawana, H. Shindou, T. Shimizu, N. Kono, and J. Aoki | Anal. Chem. | 2024 | 96 | 11771-11779, https://doi.org/10.1021/acs.analchem.4c01219 |
| A lipid index for risk of hyperlipidemia caused by anti-retroviral drugs. | M. Shimura, N. H. Kuwata, A. Fujiwara, M. Taniguchi, T. Ichinose, F. Hamano, M. Uematsu, T. Inoue, S. Matsuyama, T. Suzuki, A. K. Ghosh, H. Shindou, T. Shimizu, and H. Mitsuya | Antiviral Research | 2024 | 223 | 105819, https://doi.org/10.1016/j.antiviral.2024.105819 |
| NDUFA12 as a functional target of the anticancer compound Ertredin in human hepatoma cells as revealed by label-free chemical proteomics. | S. I. Park, S. M. Cho, S. Atsumi, M. Kawada, M. Shibuya, J. Y. Lee, J. Y. Kim, and H. J. Kwon | J. Proteome Res. | 2024 | 23 | 130-141, doi: org/10.1021/acs.jproteome.3c00471 |
| Reclassification of a reveromycin-producer and the proposals of Actinacidiphila reveromycinica sp. nov. and Actinacidiphila acidipaludis comb. nov. | H. Komaki, H. Takagi, S. Takahashi, and H. Osada | Biosci Biotechnol Biochem | 2024 | 88 | 689-695, https://doi.org/10.1093/bbb/zbae032 |
| Identification of a family of species-selective complex I inhibitors as potential anthelmintics. | T. Davie, X. Serrat, L. Imhof, J. Snider, I. Sagljar, J. Keiser, H. Hirano, N. Watanabe, H. Osada, and A. G. Fraser | Nat Commun. | 2024 | 15 | 3367. https://doi.org/10.1038/s41467-024-47331-3 |
| Macrophage/microglia-producing transient increase of platelet-activating factor is involved in neuropathic pain. | S. Yamamoto, T. Hashidate-Yoshida, Y. Yoshinari, T. Shimizu, and H. Shindou | iScience | 2024 | 27 | https://doi.org/10.1016/j.isci.2024.109466 |
| Inhibition of kynurenine production by N, O-substituted hydroxylamine derivatives. | M. Iijima, Y. Otsuka, S. Ohba, and I. Momose | Bioorg. Med. Chem. Lett. | 2024 | 106 | 129731, doi: 10.1016/j.bmcl.2024.129731. |
| Synthesis of heteroaromatic-fused cyclic β-amino acids by rhodium-catalyzed electrophilic amination. | R. Manoharan, Y. Asada, H. Noda, and M. Shibasaki | Synthesis | 2024 | 56 | 1563-1575, DOI: 10.1055/a-2282-7450 |
| Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies. | T. Arimori , E. Mihara, H. Suzuki, T. Ohishi, T. Tanaka, M. K. Kaneko, J.Takagi, and Y. Kato | Structure | 2024 | 32 | 536-549, https://doi.org/10.1016/j.str.2024.02.007 |
| Direct catalytic enantioselective conjugate addition of α‑substituted benzyl nitriles to alkyl acrylates. | S. Samanta, J. Cui, Y. Otsuka, T. Watanabe, and M. Shibasaki | Org. Lett. | 2024 | 26 | 2255-2259, https://doi.org/10.1021/acs.orglett.4c00427 |
| Impact of perinatal maternal docosahexaenoic acid-containing phospholipid synthesis on offspring growth and neurological symptoms. | A. Kanatani, D. Hishikawa, K. Nagata, F. Hamano. K. Nakano, T. Okamura, T. Shimizu, H. Shindou, T. Nagamatsu, and K. Yanagida | bioRxiv | 2024 | https://doi.org/10.1101/2024.01.06.574487 | |
| Lysophospholipid acyltransferase 9 promotes emphysema formation via platelet-activating factor. | H. Murano, S. Inoue, T. H. Yoshida, H. Shindou, T. Shimizu, Y. Otaki, Y. Minegishi, T. Kitaoka, M. Futakuchi, A. Igarashi, M. Nishiwaki, T. Nemoto, M. Sato, M. Kobayashi, K. Sato, T. Hanawa, O. Miyazaki, and M. Watanabe | Am. J. Respir. Cell Mol. Biol. | 2024 | 70 | https://doi.org/10.1165/rcmb.2023-0253OC |
| Precursor-directed biosynthesis and biological activity of tripropeptin Cpip, a new tripropeptin C analog containing pipecolic acid. | H. Hashizume, R. Sawa, Y. Kubota, S. Adachi, S. Harada, and M. Igarashi | J. Antibiot. | 2024 | 77 | 238-244, https://doi.org/10.1038/s41429-024-00703-9 |
| Analysis of the valgamicin biosynthetic pathway reveals a general mechanism for cyclopropanol formation across diverse natural product scaffolds. | R. F. Little, F. Trottmann, H. Hashizume, M. Preissler, S. Unger, R. Sawa, H. Kries, S. Pidot, M. Igarashi, and C. Hertweck | ACS Chem. Biol. | 2024 | 19 | 660-668, https://doi.org/10.1021/acschembio.3c00648 |
| A cancer-specific monoclonal antibody against HER2 exerts antitumor activities in human breast cancer xenograft models. | M. K. Kaneko., H. Suzuki, T. Ohishi, T. Nakamura, T. Tanaka, and Y. Kato | Int. J. Mol. Sci. | 2024 | 25 | 1941. doi: 10.3390/ijms25031941. |
| Catenulopyrizomicins, new anti-Hepatitis B virus compounds, from the rare actinomycete Catenuloplanes sp. MM782L-181F7. | M. Yamasaki, R. Sawa, H. Muramatsu, Y. Yamamoto, M. Umekita, Y. Kubota, Y. Kanegae, and M. Igarashi | J. Antibiot. | 2024 | 77 | 85-92. doi: 10.1038/s41429-023-00681-4. |
| A cancer-specific monoclonal antibody against podocalyxin exerted antitumor activities in pancreatic cancer xenografts. | H. Suzuki, T. Ohishi, T. Tanaka, M. K. Kaneko, and Y. Kato | Int J. Mol. Sci. | 2024 | 25 | 161. https://doi.org/10.3390/ijms25010161 |