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Title Authors Journal Year Vol Pages
Claudin-11 enhances invasive and metastatic abilities of small-cell lung cancer through MT1-MMP activation. S. Sakamoto, H. Inoue, T. Takino, Y. Kohda, J. Yoshida, S. Ohba, I. Usami, T. Suzuki, M. Kawada, and M. Hatakeyama Cancer Science 2025 doi: 10.1111/cas.70038.
Creation of a macrolide antibiotic against non-tuberculous Mycobacterium using late-stage boron-mediated aglycon delivery. Y. Isozaki, T. Makikawa, K. Kimura, D. Nishihara, M. Fujino, Y. Tanaka, C. Hayashi, Y. Ishizaki, M. Igarashi, T. Yokoyama, K. Toshima, and D.Takahashi Sci Adv. 2025 11 eadt2352. doi: 10.1126/sciadv.adt2352.
Discovery of niclosamide as a p300/transcription factor protein-protein interaction inhibitor. D. Fitriastuti, K. Miura, S. Okada, H. Hirano, H. Osada, and H. Nakamura Bioorg Med Chem. 2025 121 118114. doi: 10.1016/j.bmc.2025.118114.
Novobiocin primarily targets ParE in Neisseria gonorrhoeae. Y. Ishizaki, C. Hayashi, K. Matoba, and M. Igarashi J. Antibiot. 2025 78 159-165, https://doi.org/10.1038/s41429-024-00797-1
BIL7 enhances plant growth by regulating the transcription factor BIL1/BZR1 during brassinosteroid signaling. T. Miyaji, A. Yamagami, Y. Nakamura, K. Nishida, R. Tachibana, S. Surina, S. Fujioka, M. G. Hourquet, S. M. Garcia, S. Nosaki, T. Miyakawa, M. Tanokura, M. Matsui, H. Osada, K. Shinozaki, T. Asami, and T. Nakano The Plant Journal 2025 121 e17212, doi: 10.1111/tpj.17212
Attenuated growth factor signaling during cell death initiation sensitizes membranes towards peroxidation. A. Gollowitzer, H. Pein, Z. Rao, L. Waltl, L. Bereuter, K. Loeser, T. Meyer, V. Jafari, F. Witt, R. Winkler, F. Su, S. Große, M. Thürmer, J. Grander, M. Hotze, S. Harder, L. Espada, A. Magnutzki, R. Gstir, C. Weinigel, S. Rummler, G. Bonn, J. Pachmayr, M. Ermolaeva, T. Harayama, H. Schlüter, C. Kosan, R. Heller, K. Thedieck, M. Schmitt, T. Shimizu, J. Popp, H. Shindou, M. Kwiatkowski, and A. Koeberle Nature Communications 2025 16 1774, https://doi.org/10.1038/s41467-025-56711-2
Identification of glycogen synthase kinase 3alpha/beta as a host factor required for hepatitis B virus transcription using high-throughput screening. H. Nishitsuji, Y. Naito, Y. Murakami, M. Sugiyama, M. Mizokami, I. Shoji, T. Murata, and K. Shimotohno Hepatology 2025 doi: 10.1097/HEP.0000000000001239.
Direct catalytic asymmetric conjugate addition of benzofuran-3(2H)-ones to α,β-unsaturated thioamides: stereodivergent synthesis of rocaglaol.
S. Samanta, H. Noda,T. Watanabe, J. Cui, and M. Shibasaki Angewandte Chemie International Edition 2025 64 e202415805. doi: 10.1002/anie.202415805.
Antitumor activities of a humanized cancer-specific anti-HER2 monoclonal antibody, humH2Mab-250 in human breast cancer xenografts. M. K. Kaneko, H. Suzuki, T. Ohishi, T. Nakamura, M. Yanaka, T. Tanaka, and Y. Kato Int. J. Mol. Sci. 2025 26 1079, https://doi.org/10.3390/ijms26031079
Chemical biology research in RIKEN NPDepo aimed at agricultural applications. H. Osada Proc. Jpn. Acad., Ser. B 2025 101 8~31, http://dx.doi.org/10.2183/pjab.101.003
Mechanisms of autophagosome formation. Y. Fujioka and N. N. Noda Proc. Jpn. Acad., Ser. B 2025 101 32-40, http://dx.doi.org/10.2183/pjab.101.005
DiQuinoline-MonoQuinazoline: a flat proton binder and its application as a polyaromatic hydrocarbon scavenger and G4 ligand. T. Karimata, W. Xu, and N. Kumagai Chem. Eur. J. 2025 31 e202404335, doi.org/10.1002/chem. 202404335
Thiazoplanomicin, a new thiazolyl peptide antibiotic from the leaf-litter actinomycete Actinoplanes sp. MM794L-181F6. Y. Takehana, H. Muramatsu, M. Hatano, Y. Ishizaki, M. Umekita, Y.Shibuya, C. Hayashi, T. Kimura, T. Takeuchi, K. Shimuta, R. Sawa, and M. Igarashi J. Antibiot. 2025 78 14-25, doi: 10.1038/s41429-024-00783-7.
Aspirin modulates generation of procoagulant phospholipids in cardiovascular disease, by regulating LPCAT3. M. B. Protty, V. J. Tyrrell, A. A. Hajeyah, B. Morgan, D. Costa, Y. Li, A. Choudhury, R. Mitra, D. Bosanquet, A. Reed, I. K. Denisenko, K. Nagata, H. Shindou, B. F. Cravatt, A. W. Poole, T. Shimizu, Z. Yousef, P. W. Collins, and V. B. O’Donnell Journal of Lipid Research 2025 66 100727, https://doi.org/10.1016/j.jlr.2024.100727
Re-evaluation of the canonical PAF pathway in cutaneous anaphylaxis. T. Suzuki, Y. Taketomi, K. Yanagida, T. Y. Hashidate, T. Nagase, M. Murakami, T. Shimizu, and H. Shindou BBA-Molecular and Cell Biology of Lipids 2025 1870 159563, doi.org/10.1016/j.bbalip.2024.159563