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Title Authors Journal Year Vol Pages
A guanine derivative as a new MEK inhibitor produced by Streptomyces sp. MK63-43F2. M. Iijima, Yuji Kubota, R. Sawa, Yumiko Kubota, M. Hatano, M. Igarashi, M. Kawada, I. Momose, M. Takekawa and M. Shibasaki J. Antibiot. 2018 71 135-138
Catalytic asymmetric synthesis of α-trifluoromethylated carbinols: A case study of tertiary propargylic alcohols. H. Noda, N. Kumagai, M.Shibasaki
Asian J. Org. Chem. 2018 in press
Dihydroorotate dehydrogenase as a target for the development of novel Helicobacter pylori-specific antimicrobials.
T. Ohishi, DK. Inaoka, K. Kita, M. Kawada Chem. Pharm. Bull. 2018 66 1-4
Microbial metabolites and derivatives targeted at inflammation and bone diseases therapy: chemistry, biological activity and pharmacology. H. Adachi, K. Nakae, S. Sakamoto, C. Nosaka, S. Atsumi, M. Shibuya, N. Higashi, M. Nakajima, T. Irimura, Y. Nishimura
J. Antibiot. 2018 71 60-71
Conquering amide planarity: structural distortion and its hidden reactivity.
S. Adachi, N. Kumagai, M.Shibasaki Tetrahedron Lett. 2018 Accepted
Novel approaches for identification of anti-tumor drugs and new bioactive compounds. M. Kawada, S. Atsumi, S. Wada and S. Sakamoto
J. Antibiot. 2018 71 39-44
Valgamicin C, a novel cyclic depsipeptide containing the unusual amino acid cleonine, and related valgamicins A, T and V produced by Amycolatopsis sp. ML1-hF4. H. Hashizume, K. Iijima, K. Yamashita, T. Kimura, S. Wada, R. Sawa and M. Igarashi J.Antibiot. 2018 71 129-134
Catalytic oligopeptide synthesis. Z. Liu, H. Noda, M. Shibasaki and N. Kumagai
Org. Lett. 2018 20 612-615
Direct catalytic asymmetric mannich-type reaction en route to α-hydroxy-β-amino acid derivatives. B. Sun, R. Pluta, N. Kumagai and M. Shibasaki
Org. Lett. 2018 20 526-529
Heterogeneous heterobimetallic catalysis enabling expeditious access to CF3 containing vic-amino alcohols. T. Karasawa, N. Kumagai and M. Shibasaki Org. Lett. 2018 20 308-311
Direct catalytic asymmetric aldol reaction of thioamide with an α-vinyl appendage. J. Cui, A. Ohtsuki, T. Watanabe, N. Kumagai and M. Shibasaki Chem. Eur. J. 2018 Accepted
Biophysical characterization of Atg11, a scaffold protein essential for selective autophagy in yeast. H. Suzuki, H and N. N. Noda FEBS Open Bio. 2018 8 110-116
Autophagy-regulating protease Atg4: structure, function, regulation and inhibition. T. Maruyama and N. N. Noda J. Antibiot. 2018 71 72-78
Thieme chemistry journals awardees – Where are they now?
Bis(2-pyridyl)amides as readily cleavable amides under catalytic, neutral, and room-temperature conditions.
S. Adachi, N. Kumagai and M. Shibasaki Synlett 2018 29 301-305
Synthetic studies of viridiofungins, broad-spectrum antifungal agents and serine palmitoyl transferase inhibitors. N. Kumagai and M. Shibasaki J. Antibiot. 2018 71 53-59
In vivo efficacy of β-lactam/tripropeptin C in a mouse septicemia model and the mechanism of reverse β-lactam resistance in methicillin-resistant Staphylococcus aureus mediated by tripropeptin C. H. Hashizume1, Y. Takahashi, T. Masuda, S. Ohba, T. Ohishi, M. Kawada and M. Igarashi J Antibiot. 2018 71 79-85