Chemistry DivisionLaboratory of Molecular Structure Analysis

Research Outline

The Laboratory of Molecular Structure Analysis is mainly engaged in the structural analysis of various biologically active substances, their derivatives, and synthetic compounds by using analytical techniques such as nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry (MS), and single-crystal X-ray crystallography.

Members

Laboratory Head Ryuichi Sawa

Researcher Shinya Adachi

Researcher Kiyoko Iijima

Researcher Tomoyuki Kimura

Researcher Tatsuro Maruyama

Researcher Yumiko Kubota

One more Technical Staff

Themes

Metabolomic analysis of microbial metabolites and structural studies of novel bioactive substances

Theme outlines

1. Metabolomic analysis of microbial metabolites and structural studies of novel bioactive substances

Microbial secondary metabolites have diverse chemical structures and biological activities. The discovery of new bioactive substances has become very difficult because of the numerous types of materials that have been found by intensive screening over a long period of time. We have carried out metabolome analysis using high resolution and high accuracy LC-MS apparatus, and rapid identification of known substances (dereplication) and structural analysis of novel bioactive substances.