化合物一覧
Dephostatin
Producing organism:
Streptomyces sp. MJ742-NF5
Activity:
Tyrosine phosphatase inhibitorAntibacterial,Cytotoxic
Clinical use:
-
Class no:
5 Reference(s)
Streptomyces sp. MJ742-NF5
Tyrosine phosphatase inhibitorAntibacterial,Cytotoxic
-
5 Reference(s)
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| Title | Author | Journal | Year | Volume | Page |
|---|---|---|---|---|---|
| Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. I. Taxonomy, isolation, and characterization. | M. Imoto; H. Kakeya; T. Sawa; C. Hayashi; M. Hamada; T. Takeuchi; K. Umezawa | J. Antibiotics | 1993 | 46 | 1342-1346 |
| Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. II. Structure determination. | H. Kakeuya; M. Imoto; Y. Takahashi; H. Naganawa; T. Takeuchi; K. Umezawa | J. Antibiotics | 1993 | 46 | 1716-1719 |
| Total synthesis of dephostatin, a novel protein tyrosine phosphatase inhibitor. | T. Watanabe; T. Takeuchi; M. Otsuka; K. Umezawa | J. Chem. Soc., Chem. Commun. | 1994 | 4 | 437-438 |
| Synthesis and protein tyrosine phosphatase inhibitory activity of dephostatin analogs. | T. Watanabe; T. Takeuchi; M. Otsuka; S. Tanaka; K. Umezawa | J. Antibiotics | 1995 | 48 | 1460-1466 |
| Enhancement or induction of neurite formation by a protein tyrosine phosphatase inhibitor, 3,4-dephostatin, in growth factor-treated PC12h cells. | S. Fujiwara; T. Watanabe; T. Nagatsu; J. Gohda; M. Imoto; K. Umezawa | Biochem. Biophys. Res. Commun. | 1997 | 238 | 213-217 |