化合物一覧

Conagenin

Conagenin_1

Producing organism:

Streptomyces roseosporus MI696-AF3

Activity:

Immunomodulator

Clinical use:

-

Class no:

7 Reference(s)

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Title Author Journal Year Volume Page
Conagenin, a low molecular weight immunomodulator produced by Streptomyces roseosporus. T. Yamashita; M. Iijima; H. Nakamura; K. Isshiki; H. Naganawa; S. Hattori; M. Hamada; M. Ishizuka; T. Takeuchi; Y. Iitaka J. Antibiotics 1991 44 557-559
T cell activation by conagenin in mice. M. Kawatsu; T. Yamashita; M. Osono; M. Ishizuka; T. Takeuchi J. Antibiotics 1993 46 1687-1691
Effect of conagenin in tumor bearing mice. Antitumor activity, generation of effector cells and cytokine production. M. Kawatsu; T. Yamashita; M. Osono; T. Masuda; M. Ishizuka; T. Takeuchi J. Antibiotics 1993 46 1692-1698
Effect of conagenin on thrombocytopenia induced by antitumor agents in mice. M. Kawatsu; T. Yamashita; M. Ishizuka; T. Takeuchi J. Antibiotics 1994 47 1123-1129
Improvement of efficacy of antitumor agents by conagenin. M. Kawatsu; T. Yamashita; M. Ishizuka; T. Takeuchi J. Antibiotics 1995 48 222-225
Improvement of intestinal toxicity of 5-fluorouracil by conagenin, a low molecular immunomodulator. M. Kawatsu; T. Yamashita; M. Ishizuka; T. Takeuchi Anticancer Research 1996 16 2937-2942
Modulation by conagenin of inflammatory mediator productions in mice given 5-fluorouracil. M. Kawatsu; T. Yamashita; M. Ishizuka; T. Takeuchi Anticancer Research 1997 17 917-922