化合物一覧

Arphamenine

Arphamenine_1

Producing organism:

Chromobacterium violaceum BMG361-CF4

Activity:

Aminopeptidase B inhibitor

Clinical use:

-

Class no:

8 Reference(s)

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Title Author Journal Year Volume Page
Arphamenine A and B, new inhibitors of aminopeptidase B, produced by bacteria. H. Umezawa; T. Aoyagi; S Ohuchi; A. Okuyama; H. Suda; T. Takita; M. Hamada; T. Takeuchi J. Antibiotics 1983 36 1572-1575
The structure of arphamenine A and B. S. Ohuchi; H. Suda; H. Naganawa; T. Takita; T. Aoyagi; H. Umezawa; H. Nakamura; Y. Iitaka J. Antibiotics 1983 36 1576-1580
Biosynthetic studies of arphamenines A and B. S. Ohuchi; A. Okuyama; H. Naganawa; T. Aoyagi; H. Umezawa J. Antibiotics 1984 37 518-521
The improvement of productivity and selective production of arphamenines by addition of their biosynthetic precursors. S. Ohuchi; A. Okuyama; K. Kawamura; T. Aoyagi; H. Umezawa Agric. Biol. Chem. 1984 48 1661-1662
Structure-activity relationships among derivatives of arphamenines, inhibitors of aminopeptidase B. S. Ohuchi; H. Suda; H. Naganawa; K. Kawamura; T. Aoyagi; H. Umezawa J. Antibiotics 1984 37 1741-1743
Mitogenic potentials of bestatin, amastatin, arphamenines A and B, FK-156 and FK-565 on spleen lymphocytes. N. Weissmann; G. Leyhausen; A. Maidhof; W. Tanaka; H. Umezawa; W. E. G. Mueller J. Antibiotics 1985 38 772-778
Isolation of intermediates of arphamenine A biosynthesis. A. Okuyama; S. Ohuchi; T. Tanaka; H. Naganawa; T. Aoyagi; H. Umezawa Biochemistry International 1986 12 361-366
Cell-free biosynthesis of arphamenine A. A. Okuyama; S. Ohuchi; T. Tanaka; T. Aoyagi; H. Umezawa Biochemistry International 1986 12 485-491