Compounds
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| Title | Author | Journal | Year | Volume | Page |
|---|---|---|---|---|---|
| Studies on inactivation of kanamycin and resistances of E. coli. | M. Okanishi; S. Kondo; Y. Suzuki; S. Okamoto; H. Umezawa | J. Antibiotics | 1967 | 20 | 132-135 |
| Isolation and structure of kanamycin inactivated by a cell free system of kanamycin-resistant E. coli. | H. Umezawa; M. Okanishi; R. Utahara; K. Maeda; S. Kondo | J. Antibiotics | 1967 | 20 | 136-141 |
| Phosphorylative inactivation of aminoglycosidic antibiotics by Escherichia coli carrying R factor. | H. Umezawa; M. Okanishi; S. Kondo; K. Maeda; R. Utahara; S. Mitsuhashi | Science | 1967 | 157 | 1559-1561 |
| Miscoding activities of biologically inactivated kanamycins. | M. Hori; H. Umezawa | J. Antibiotics | 1967 | 20 | 386-387 |
| Inactivation of kanamycin by E. coli carrying R factor and structures of the inactivated forms. | H. Umezawa; M. Okanishi; S. Kondo | 5th International Congress of Chemotherapy, Vienna | 1967 | ||
| Isolation of kanamycin and paromamine inactivated by E. coli carrying R factor. | S. Kondo; M. Okanishi; R. Utahara; K. Maeda; H. Umezawa | J. Antibiotics | 1968 | 21 | 22-29 |
| Progess in the fundamental studies on kanamycin. (Japanese) | H. Umezawa | Nippon Ishikai Zasshi | 1967 | 58 | 1329-1341 |
| The crystal structure of kanamycin. | G. Koyama | Tetrahedron Letters | 1968 | 1875-1879 | |
| Progress of fundamental studies on kanamycin. I. The structure and the biosynthesis; II. Structure-activity relationship and mechanism of the resistance. | H. Umezawa | Asian Medical Journal | 1968 | 11 | 69-77 |
| Inactivation of kanamycin, neomycin, and streptomycin by enzymes obtained in cells of Pseudomonas aeruginosa. | O. Doi; M. Ogura; N. Tanaka; H. Umezawa | Appl. Microbiology | 1968 | 16 | 1276-1281 |
| Inactivation and phosphorylation of kanamycin by drug-resistant Staphylococcus aureus. | O. Doi; M. Miyamoto; N. Tanaka; H. Umezawa | Appl. Microbiology | 1968 | 16 | 1282-1284 |
| Phosphorylation and inactivation of kanamycin by Pseudomonas aeruginosa. | H. Umezawa; O. Doi; M. Ogura; S. Kondo; N. Tanaka | J. Antibiotics | 1968 | 21 | 154-155 |
| Studies on the biosynthesis of kanamycins. I. Incorporation of 14C-glucose or 14C-glucosamine into kanamycins and kanamycin-related compounds. | M. Kojima; Y. Yamada; H. Umezawa | Agric. Biol. Chem. | 1968 | 32 | 467-473 |
| Studies on the biosynthesis of kanamycins. II. Incorporation of the radioactive degradation products of kanamycin A or related metabolites into kanamycin A. | M. Kojima; Y. Yamada; H. Umezawa | Agric. Biol. Chem. | 1969 | 33 | 1181-1185 |
| Purification and properties of kanamycin phosphorylating enzyme from Pseudomonas aeruginosa. | O. Doi; S. Kondo; N. Tanaka; H. Umezawa | J. Antibiotics | 1969 | 22 | 273-282 |
| Effects of kanamycin on protein synthesis: Inhibition of peptide chains. | J. Suzuki; T. Kunimoto; M. Hori | J. Antibiotics | 1970 | 23 | 99-101 |
| Studies on kanamycin related compounds produced during fermentation by mutants of Streptomyces kanamyceticus. | M. Murase; T. Ito; S. Fukatsu; H. Umezawa | Progress in Antimicrobial and Anticancer Chemotherapy | 1970 | II | 1098 |
| Adenylyl dideoxykanamyci B, a product of the inactivation of dideoxykanamycin B by Escherichia coli carrying R factor. | M. Yagisawa; H. Naganawa; S. Kondo; M. Hamada; T. Takeuchi; H. Umezawa | J. Antibiotics | 1971 | 24 | 911-912 |
| Kanamycin derivatives effective against resistant organisms. | H. Umezawa; T. Takeuchi; T. Tsuchiya; S. Umezawa | Proceedings of the VIIth International Congress of Chemotherapy, Prague | 1971 | ||
| Kanamycin phosphotransferase I: Mechanism of cross resistance between kanamycin and lividomycin. | H. Umezawa; H. Yamamoto; M. Yagisawa; S. Kondo; T. Takeuchi; Y. A. Chabbert | J. Antibiotics | 1973 | 26 | 407-411 |
| Syntheses of isoseryl derivatives of kanamycins and their antibacterial activities. | S. Kondo; K. Iinuma; M. Hamada; K. Maeda; H. Umezawa | J. Antibiotics | 1974 | 27 | 90-93 |
| Elimination of the ability of a kanamycin-producing strain to biosynthesize deoxystreptamine moiety by acriflavine. | K. Hotta; Y. Okami; H. Umezawa | J. Antibiotics | 1977 | 30 | 1146-1149 |
| Syntheses and properties of kanamycin C derivatives active against resistant bacteria. | S. Kondo; T. Miyasaka; K. Yoshida; K. Iinuma; H. Umezawa | J. Antibiotics | 1977 | 30 | 1150-1152 |
| Discoveries of kanamycin and bleomycin -Chemistry of Antibiotics- (Japanese) | H. Umezawa | Kagaku Kyoiku | 1978 | 26 | 434-442 |
| Syntheses and properties of the 6"-deoxy or 4",6"-dideoxy derivatives of the kanamycin antibiotics. | T. Miyasaka; D. Ikeda; S. Kondo; H. Umezawa | J. Antibiotics | 1980 | 33 | 527-532 |
| Stereospecific transformation of D-sugar to L-sugar in complex aminoglycoside. Synthesis of a kanamycin B analog having 2,6-diamino-2,4,6-trideoxy-L-arabino-hexopyranose. | Y. Nishimura; H. Umezawa; S. Umezawa | Tetrahedron Letters | 1981 | 22 | 77-80 |
| Combimicins, new kanamycin derivatives bioconverted by some Micromonosporas. | Y. Oka; H. Ishida; M. Morioka; Y. Numasaki; T. Yamafuji; T. Osono; H. Umezawa | J. Antibiotics | 1981 | 34 | 777-781 |
| Resistance mechanisms of kanamycin-, neomycin-, and streptomycin-producing streptomycetes to aminoglycoside antibiotics. | K. Hotta; H. Yamamoto; Y. Okami; H. Umezawa | J. Antibiotics | 1981 | 34 | 1175-1182 |
| Regiospecific introduction of a branched-chain to kanamycin B and stereospecific transformation of the 2,6-diamino-2,6-dideoxy-D-glucopyranosyl moiety into 2,6-diamino-2,6-tetradeoxy-3-C-methyl-L-arabino or lyxo-hexopyranosyl, or 2-amino-2,3,4,6-tetradeoxy-5- C-methyl-L-threohexopyranosyl. | Y. Nishimura; S. Umezawa | Tetrahedron Letters | 1982 | 23 | 81-84 |
| A novel deaminative cyclization of aminoglycoside. Synthesis of a kanamycin B variant having 2-oxa-5-azabicyclo[2,2,2]oct-1,5-diene ring. | Y. Nishimura; S. Umezawa | Tetrahedron Letters | 1982 | 23 | 85-86 |
| A predominant role of amino groups in the antibacterial action of aminoglycosides: Synthesis of hexa- and heptadeoxykanamycin derivatives. | H. Umezawa; H. Iwasawa; D. Ikeda; S. Kondo | J. Antibiotics | 1983 | 36 | 1087-1091 |
| Synthesis of 1-N-(2-aminoethanesulfonyl)kanamycins and related aminoglycoside antibiotics. | E. Akita; Y. Horiuchi; T. Miyazawa; H. Umezawa | J. Antibiotics | 1983 | 36 | 745-748 |