Compounds

Conagenin

Conagenin_1

Producing organism:

Streptomyces roseosporus MI696-AF3

Activity:

Immunomodulator

Clinical use:

-

Class no:

7 Reference(s)

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Title	Author	Journal	Year	Volume	Page
Conagenin, a low molecular weight immunomodulator produced by Streptomyces roseosporus.	T. Yamashita; M. Iijima; H. Nakamura; K. Isshiki; H. Naganawa; S. Hattori; M. Hamada; M. Ishizuka; T. Takeuchi; Y. Iitaka	J. Antibiotics	1991	44	557-559
T cell activation by conagenin in mice.	M. Kawatsu; T. Yamashita; M. Osono; M. Ishizuka; T. Takeuchi	J. Antibiotics	1993	46	1687-1691
Effect of conagenin in tumor bearing mice. Antitumor activity, generation of effector cells and cytokine production.	M. Kawatsu; T. Yamashita; M. Osono; T. Masuda; M. Ishizuka; T. Takeuchi	J. Antibiotics	1993	46	1692-1698
Effect of conagenin on thrombocytopenia induced by antitumor agents in mice.	M. Kawatsu; T. Yamashita; M. Ishizuka; T. Takeuchi	J. Antibiotics	1994	47	1123-1129
Improvement of efficacy of antitumor agents by conagenin.	M. Kawatsu; T. Yamashita; M. Ishizuka; T. Takeuchi	J. Antibiotics	1995	48	222-225
Improvement of intestinal toxicity of 5-fluorouracil by conagenin, a low molecular immunomodulator.	M. Kawatsu; T. Yamashita; M. Ishizuka; T. Takeuchi	Anticancer Research	1996	16	2937-2942
Modulation by conagenin of inflammatory mediator productions in mice given 5-fluorouracil.	M. Kawatsu; T. Yamashita; M. Ishizuka; T. Takeuchi	Anticancer Research	1997	17	917-922