Compounds

Benadrostin

Benadrostin_1

Producing organism:

Streptomyces flavovirens MH499-O

Activity:

F1

Clinical use:

Poly(ADP-ribose) synthetase inhibitor

Class no:

2 Reference(s)

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Title Author Journal Year Volume Page
Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by Actinomycetes. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. T. Aoyagi; S. Yoshida; S. Harada; A. Okuyama; C. Nakayama; T. Yoshida; M. Hamada; T. Takeuchi; H. Umezawa J. Antibiotics 1988 41 1009-1014
Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. II. Structure determination. S. Yoshida; H. Naganawa; T. Aoyagi; T. Takeuchi; H. Umezawa J. Antibiotics 1988 41 1015-1018