Compounds

Intervenolin

Intervenolin_1

Producing organism:

Nocardia sp.ML96-86F2

Activity:

Antitumor and anti-Helicobacter pylori

Clinical use:

-

Class no:

3 Reference(s)

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Title	Author	Journal	Year	Volume	Page
Intervenolin, a new antitumor compound with anti-Helicobacter pylori activity, from Nocardia sp. ML96-86F2.	M. Kawada, H. Inoue, S. Ohba, M. Hatano, M. Amemiya, C. Hayashi, I. Usami, H. Abe, T. Watanabe, N. Kinoshita, M. Igarashi, T. Masuda, D. Ikeda and A. Nomoto.	J. Antibiot.	2013	66	543-548.
Structure-activity relationship study of intervenolin derivatives: synthesis, antitumor and anti-Helicobacter Pylori activities.	H. Abe, M. Kawada, H. Inoue, S. Ohba, T. Masuda, C. Hayashi, M. Igarashi, A. Nomoto, T. Watanabe and M. Shibasaki.	Tetrahedron	2013	69	7608-7617.
Synthesis of intervenolin, an antitumor natural quinolone with unusual substituents.	H. Abe, M. Kawada, H. Inoue, S. Ohba, A. Nomoto, T. Watanabe and M. Shibasaki.	Org. Lett.	2013	15	2124-2127.