Compounds

Decalpenic acid

Decalpenic acid_1

Producing organism:

Penicillium verruculosum CR37010

Activity:

Osteoblastogenesis inducer (Activation of Retinoic acid receptors)

Clinical use:

-

Class no:

2

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Title Author Journal Year Volume Page
Decalpenic acid, a novel small molecule from Penicillium verruculosum CR37010, induces early osteoblastic markers in pluripotent mesenchymal cells. S. Sakamoto, F. Kojima, M. Igarashi, R. Sawa, M. Umekita, Y. Kubota, K. Nakae, S. Yamaguchi, H. Adachi, Y. Nishimura and Y. Akamatsu J. Antibiot. 2010 63 703-706.
Decalpenic acid induces early osteoblastic markers in pluripotent
mesenchymal cells via activation of retinoic acid receptor gamma.		 S. Sakamoto, F. Kojima, I. Momose, M. Kawada, H.
Adachi and Y. Nishimura.		 Biochem. Biophys. Res. Commun. 2012 422 751-757.