Compounds
Thiazinotrienomycin
Producing organism:
Streptomyces sp. MJ672-m3
Activity:
Antitumor
Clinical use:
-
Class no:
2 Reference(s)
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Title | Author | Journal | Year | Volume | Page |
---|---|---|---|---|---|
Thiazinotrienomycins, new ansamycin group antibiotics. | N. Hosokawa; H. Naganawa; H. Iinuma; M. Hamada; T. Takeuchi; T. Kanbe, and M. Hori | J. Antibiot. | 1995 | 48 | 471-478 |
(+)-Thiazinotrienomycin E: relative and absolute stereochemistry. | A. B. Smith, III; J. Barbosa; N. Hosokawa; H. Naganawa, and T. Takeuchi | Tetrahedron Letters | 1998 | 39 | 2891-2894 |
Effect of thiazinotrienomycin B, an ansamycin antibiotics, on the function of EGFR in human stomach tumor cells. | N. Hosokawa, S. Yamamoto, Y. Uehara, M. Hori, and K. S. Tsuchiya | J. Antibiot. | 1999 | 52 | 485-490 |
Anticancer and some biological activities of thiazinotrienomycin B. | N. Hosokawa, H. iinuma, T. Takeuchi, S. Sato, and T. Yamori | J. Antibiot. | 2000 | 53 | 306-308 |
New triene-ansamycins, thiazinotrienomycins F and G and a diene-ansamycin, Benzoxazomycin. | N. Hosokawa, H. Naganawa, M. Hamada, H. Iinuma, T. Takeuchi, K. S. Tsuchiya, and M. Hori | J. Antibiot. | 2000 | 53 | 886-894 |
Total synthesis of (+)-thiazinotrienomycin E. | A. B. Smith III, and W. Zehong | Organic Letters | 1999 | 1 | 1491-1494 |
Total synthesis of ansamycin antibiotic (+)-thiazinotrienomycin E. | A. B. Smith III, and W. Zehong | J. O. C. (The compound and its producing bacterial strain covered this Journal.) | 2000 | 65 | 3738-3753 |
New ansamycin derivatives generated by simultaneous mutasynthesis (Benzoxazomycin) | Y. N. Song, R. H. Jiao, W. J. Zhang, G. Y. Zhao, H. Dou, R. Jiang, A. H. Zhang, Y. Y. Hou, S. F. Bi, H. M. Ge, and R. X. Tan | Organic Letters | 2015 | 17 | 556-559 |
Narural occurrence, bioactivity, and biosynthesis of triene-ansamycins | X. Yang, W. Wu, H. Li, M. Zhang, Z, Chu, X. Wang, and P. Sun | European Journal of Medicinal Chemistry | 2022 | 244 | 114815, https:/doi.org/10.1016/j.emech.2022.114815 |
Thiazinotrienomycin, a carcinostatic antibiotic, and its production method | T. Takeuchi, M. Hori, M. Hamada, H. Naganawa, and N. Hosokawa | JP3502655B2 | 1994 | ||
Thiazinotrienomycins F, G and Benzoxazomycin, a carcinostatic antibiotics | T. Takeuchi, M. Hori, M. Hamada, H. Naganawa, and N. Hosokawa | JP4495817B2 | 2000 |