Compounds

Phosphoramidon

Phosphoramidon_1

Producing organism:

Streptomyces tanashiensis MD706-Y4

Activity:

Thermolysin inhibitorInhibitor of endothelin converting enzyme

Clinical use:

-

Class no:

4 Reference(s)

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Title	Author	Journal	Year	Volume	Page
A new microbial metabolite phosphoramidon: Isolation and structure.	S. Umezawa; K. Tatsuta; O. Izawa; T. Tsuchiya	Tetrahedron Letters	1972	13	97-100
A thermolysin inhibitor produced by Actinomycetes: Phosphoramidon.	H. Suda; T. Aoyagi; T. Takeuchi; H. Umezawa	J. Antibiotics	1973	26	621-623
Inhibitory effects of phosphoramidon on neutral metallo-endopeptidases and its application on affinity chromatography.	T. Komiyama; T. Aoyagi; T. Takeuchi; H. Umezawa	Biochem. Biophys. Res. Commun.	1975	65	352-357
Studies on inhibitory effect of phosphoramidon and its analogs on thermolysin.	T. Komiyama; H. Suda; T. Aoyagi; T. Takeuchi; H. Umezawa; K. Fujimoto; S. Umezawa	Arch. Biochem. Biophys.	1975	171	727-731