Compounds

Phleomycins

Phleomycins_1

Producing organism:

Streptomyces verticillus

Activity:

Antitumor

Clinical use:

-

Class no:

10 Reference(s)

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Title Author Journal Year Volume Page
Inhibition of resistant dysentery bacilli by phleomycin. T. Takeuchi; M. Ishizuka; Y. Yamzaki; H. Umezawa J. Antibiotics 1963 16 172
Separation of phleomycin components and their properties. T. Ikekawa; F. Iwami; H. Hiranaka; H. Umezawa J. Antibiotics 1964 17 194-199
Studies on antitumor effect of phleomycin. H. Umezawa; M. Hori; M. Ishizuka; T. Takeuchi J. Antibiotics 1962 15 274-275
Studies on antitumor activity, antimicrobial activity and toxicity of phleomycin. M. Ishizuka; H. Takayamma; T. Takeuchi; H. Umezawa J. Antibiotics 1966 19 260-271
Modes of action of phleomycin, bleomycin and formycin on HeLa S3 cells in synchronized culture. T. Kunimoto; M. Hori; H. Umezawa J. Antibiotics 1967 20 277-281
The structure of the sulfur-containing chromophore of phleomycin, and chemical transformation of phleomycin to bleomycin. T. Takita; Y. Muraoka; A. Fujii; H. Itoh; K. Maeda; H. Umezawa J. Antibiotics 1972 25 197-199
The chemistry of bleomycin. IX. The structures of bleomycin and phleomycin. T. Takita; Y. Muraoka; T. Yoshioka; A. Fujii; K. Maeda; H. Umezawa J. Antibiotics 1972 25 755-758
Chemistry of bleomycin. XIX. Revised structures of bleomycin and phleomycin. T. Takita; Y.Muraoka; T. Nakatani; A. Fujii; Y.Umezawa; H. Naganawa; H. Umezawa J. Antibiotics 1978 31 801-804
Bleomycin-phleomycin group antibiotics. T. Takita Advances in Natural Products Chemistry (S. Natori et al. eds.) Kodansha Scientific Co. 1981 29-38
Bleomycin-phleomycin group antibiotics. T. Takita Advances in Natural Products Chemistry (S. Natori, N. Ikegawa, M. Suzuki, eds.)Kodansha Scientific 1981 29-38