Compounds

Oxanosine

Oxanosine_1

Producing organism:

Streptomyces capreolus MG265-CF3

Activity:

Antibacterial

Clinical use:

-

Class no:

10 Reference(s)

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Title Author Journal Year Volume Page
Oxanosine, a novel nucleoside from Actinomycetes. N. Shimada; N. Yagisawa; H. Naganawa; T. Takita; M. Hamada; T. Takeuchi; H. Umezawa J. Antibiotics 1981 34 1216-1218
The X-ray structure determination of oxanosine. H. Nakamura; N. Yagisawa; N. Shimada; T. Takita; H. Umezawa; Y. Iitaka J. Antibiotics 1981 34 1219-1221
Oxanosine, a novel nucleoside from Actinomycetes. N. Yagisawa; N. Shimada; H. Naganawa; T. Takita; M. Hamada; T. Takeuchi; H. Umezawa; H. Nakamura; Y. Iitaka Nucleic Acids Research, Symposium Series No. 10 1981 55-58
Mode of action of oxanosine, a novel nucleoside antibiotic. N. Yagisawa; N. Shimada; T. Takita; M. Ishizuka; T. Takeuchi; H. Umezawa J. Antibiotics 1982 35 755-759
A facile total synthesis of oxanosine, a novel nucleoside antibiotic. N. Yagisawa; T. Takita; H. Umezawa; K. Kato; N. Shimada Tetrahedron Letters 1983 24 931-932
Synthesis of 3-deazaoxanosines, c-nucleoside isosteres of oxanosine. S. Niitsuma; K. Kato; T. Takita; H. Umezawa Tetrahedron Letters 1985 26 5785-5786
Increased sensitivity to oxanosine, a novel nucleoside antibiotic, of rat kidney cells upon expression of the integrated viral src gene. Y. Uehara; M. Hasegawa; M. Hori; H. Umezawa Cancer Research 1985 45 5230-5234
Induction by the guanosine analogue oxanosine of reversion toward the normal phenotype of K-ras-transformed rat kidney cells. O. Itoh; S. Kuroiwa; S. Atsumi; K. Umezawa; T. Takeuchi; M. Hori Cancer Research 1989 49 996-1000
Synergism between 5-fluorouracil and oxanosine in inhibiting growth of ras-expressed cells in vitro and in vivo. K. S.-Tsuchiya; Y.Moriya; M. Hori; O. Itoh; T. Takeuchi; H. Ekimoto; M. Hiratsuka J. Antibiotics 1992 45 283-285