Compounds
Leucylnegamycin
Producing organism:
Streptomyces No. M890-C2
Activity:
Antibacterial
Clinical use:
-
Class no:
14 Reference(s)
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| Title | Author | Journal | Year | Volume | Page |
|---|---|---|---|---|---|
| A new antibiotic, negamycin. | M. Hamada; T. Takeuchi, S. Kondo; Y. Ikeda; H. Naganawa; K. Maeda; Y. Okami; H. Umezawa | J. Antibiotics | 1970 | 23 | 170-171 |
| Mechanism of action of negamycin in Escherichia coli K-12. I. Inhibition of initiation of protein synthesis. | S. Mizuno; K. Nitta; H. Umezawa | J. Antibiotics | 1970 | 23 | 581-588 |
| Mechanism of action of negamycin in Escherichia coli K-12. II. Miscoding activity in polypeptide synthesis directed by synthetic polynucleotide. | S. Mizuno; K. Nitta; H. Umezawa | J. Antibiotics | 1970 | 23 | 589-594 |
| Leucylnegamycin, an antibiotic from negamycin-producing Streptomyces. | S. Kondo; H. Yamamoto; K. Maeda; H. Umezawa | J. Antibiotics | 1971 | 24 | 732-734 |
| Negamycin, a novel hydrazide antibiotic. | S. Kondo; S. Shibahara; S. Takahashi; K. Maeda; H. Umezawa; M. Ohno | J. Am. Chem. Soc. | 1971 | 93 | 6305 |
| The total syntheses of negamycin and the antipode. | S. Shibahara; S. Kondo; K. Maeda; H. Umezawa; M. Ohno | J. Am. Chem. Soc. | 1972 | 94 | 4353-4354 |
| Negamycin, a miscoding antibiotic with a unique structure. | Y. Uehara; S. Kondo; H. Umezawa; K. Suzukake; M. Hori | J. Antibiotics | 1972 | 25 | 685-688 |
| Negamycin inhibits termination of protein synthesis directed by phage f2 RNA in vitro. | Y. Uehara; M. Hori; H. Umezawa | Biochim. Biophys. Acta | 1974 | 374 | 82-95 |
| Syntheses and properties of negamycin analogs modified the d-hydroxy-β-lysine moiety. | S. Kondo; K. Iinuma; K. Yoshida; K. Yokose; Y. Ikeda; M. Shimazaki; H. Umezawa | J. Antibiotics | 1976 | 29 | 208-211 |
| Specific inhibition of the termination process of protein synthesis by negamycin. | Y. Uehara; M. Hori; H. Umezawa | Biochim. Biophys. Acta | 1976 | 442 | 251-262 |
| Structure-activity relationships among negamycin analogs. | Y. Uehara; M. Hori; S. Kondo; M. Hamada; H. Umezawa | J. Antibiotics | 1976 | 29 | 937-943 |
| Inhibitory effect of negamycin on polysomal ribosomes of Escherichia coli. | Y. Uehara; M. Hori; H. Umezawa | Biochim. Biophys. Acta | 1976 | 447 | 406-412 |
| 3-epi-Deoxynegamycin and leucyl-3-epi-deoxynegamycin produced by Streptomyces. | S. Kondo; K. Yoshida; T. Ikeda; K. Iinuma; Y. Honma; M. Hamada; H. Umezawa | J. Antibiotics | 1977 | 30 | 1137-1139 |
| Preparation of negamycin ointments. I. Possible utility of gel bases. (Japanese) | M. Kuwahara; T. Fuwa; Y. Odagiri; K. Uekama; K. Suzuki; M. Shibata; M. Hamada; S. Kondo; T. Takeuchi; H. Umezawa | Yakugaku Zasshi | 1986 | 106 | 313-319 |
| Preparation of negamycin ointments. II. Improvement in stability and antimicrobial activity. (Japanese) | M. Kuwahara; T. Fuwa; Y. Odagiri; K. Uekama; K. Suzuki; M. Shibata; M. Hamada; S. Kondo; T. Takeuchi; H. Umezawa | Yakugaku Zasshi | 1986 | 106 | 320-324 |