Compounds

Lavendustin

Lavendustin_1

Producing organism:

Streptomyces griseolavendus MI435-40F6

Activity:

Tyrosine-kinase inhibitor

Clinical use:

-

Class no:

2 Reference(s)

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Title Author Journal Year Volume Page
Isolation of a novel tyrosine kinase inhibitor, lavendustin A, from Streptomyces griseolavendus. T. Onoda; H. Iinuma; Y. Sasaki; M. Hamada; K. Isshiki; H. Naganawa; T. Takeuchi; K. Tatsuta; K. Umezawa J. Natural Products 1989 52 1252-1257
Inhibition of tyrosine kinase and epidermal growth factor receptor internalization by lavendustin A methyl ester in cultured A431 cells. T. Onoda; K. Isshiki; T. Takeuchi; K. Tatsuta; K. Umezawa Drugs Exptl. Clin. Res. 1990 16 249-253