Compounds

Istamycin

Istamycin_1

Producing organism:

Streptomyces tenjimariensis SS-939

Activity:

Antibacterial

Clinical use:

-

Class no:

18 Reference(s)

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Title Author Journal Year Volume Page
New aminoglycoside antibiotics, istamycins A and B. Y. Okami; K. Hotta; M. Yoshida; D. Ikeda; S. Kondo; H. Umezawa J. Antibiotics 1979 32 964-966
Synthesis of istamycin A. D. Ikeda; T. Miyasaka; M. Yoshida; Y. Horiuchi; S. Kondo; H. Umezawa J. Antibiotics 1979 32 1365-1366
Synthesis of demethyl derivatives of istamycin A. D. Ikeda; Y. Horiuchi; S. Kondo; H. Umezawa J. Antibiotics 1980 33 1281-1288
Studies on new aminoglyucoside antibiotics, istamcyins, from an actinomycete isolated from a marine environment. I. The use of plasmid profiels in screening antibiotic-producing streptomycetes. K. Hotta; N. Saito; Y. Okami J. Antibiotics 1980 33 1502-1509
Studies on new aminoglycoisde antibiotics, istamcyins, from an actinomycete isolated from a marine environment. II. Possible involvement of plasmid in istamycin production. K. Hotta; Y. Okami; H. Umezawa J. Antibiotics 1980 33 1510-1514
Studies on new aminoglycoside antibiotics, istamycins, from an Actinomycete isolated from a marine environment. III. Nutritional effects on istamycin production and additional chemical and biological properties of istamycins. K. Hotta; M. Yoshida; M. Hamada; Y. Okami J. Antibiotics 1980 33 1515-1520
Synthesis of the 3-O-demethyl and 2"-N-formimidoyl derivatives of istamycin B. Y. Horiuchi; D. Ikeda; S. Kondo; H. Umezawa J. Antibiotics 1980 33 1577-1580
Self-resistance of a Streptomyces which produces istamycins. H. Yamamoto; K. Hotta; Y. Okami; H. Umezawa J. Antibiotics 1981 34 824-829
Ribosomal resistance of an istamycin producer, Streptomyces tenjimariensis, to aminoglycoside antibiotics. H. Yamamoto; K. Hotta; Y. Okami; H. Umezawa Biochem. Biophys. Res. Commun. 1981 100 1396-1401
2"-N-Formimidoylistamycin A and B produced by Streptomyces tenjimariensis. S. Kondo; Y. Horiuchi; D. Ikeda; S. Gomi; K. Hotta; Y. Okami; H. Umezawa J. Antibiotics 1982 35 1104-1106
Isolation and structures of istamycins X0 and Y0. (Japanese) D. Ikeda; T. Miyasaka; S. Yoshida; Y. Horiuchi; S. Kondo; H. Umezawa J. Chem. Soc. Jpn., Chem. Indust. Chem. 1982 10 1692-1695
Horizon in 1,4-diaminocyclitol-aminoglycoside antibiotics. (Japanese) D. Ikeda; T. Miyasaka; S. Yoshida; Y. Horiuchi; S. Kondo; H. Umezawa Yuki Gosei Kagaku Kyokaishi 1982 40 902-911
Isolation and synthesis of 2"-N-formimidoylistamycins A and B, new istamycin components. Y. Horiuchi; D. Ikeda; S. Gomi; S. Kondo; H. Umezawa Carbohydrate Research 1982 109 25-31
Isolation and structures of istamycin components. D. Ikeda; Y. Horiuchi; M. Yoshida; T. Miyasaka; S. Kondo; H. Umezawa Carbohydrate Research 1982 109 33-45
Some chemical modifications of istamycin B. D. Ikeda; S. Gomi; S. Kondo; H. Umezawa J. Antibiotics 1983 36 331-334
Plasmid variability in the istamycin producing strains of Streptomyces tenjimariensis. T. Shigyo; K. Hotta; Y. Okami; H. Umezawa J. Antibiotics 1984 37 635-640
Biosynthesis of istamycins by Streptomyces tenjimariensis. K. Hotta; M. Morioka; H. Tohyama; Y. Okami Trends in Actinomycetology in Japan (Ed. Y. Koyama)Society for Actinomycetes, Japan 1989 61-64
Low toxic derivatives of istamycin B: Synthesis and preliminary evaluation. D. Ikeda; S. Gomi; M. Hamada; S. Kondo; T. Takeuchi Drugs Exptl. Clin. Res. 1992 18 205-216