Compounds
Hydroxybenanomicin
Producing organism:
Actinomadura spadix MH193-16F4
Activity:
Antifungal
Clinical use:
-
Class no:
22 Reference(s)
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| Title | Author | Journal | Year | Volume | Page |
|---|---|---|---|---|---|
| New antifungal antibiotics, benanomicins A and B from an Actinomycete. | T. Takeuchi; T. Hara; H. Naganawa; M. Okada; M. Hamada; H. Umezawa; S. Gomi; M. Sezaki; S. Kondo | J. Antibiotics | 1988 | 41 | 807-811 |
| The structures of new antifungal antibiotics, benanomicins A and B. | S. Gomi; M. Sezaki; S. Kondo; T. Hara; H. Naganawa; T. Takeuchi | J. Antibiotics | 1988 | 41 | 1019-1028 |
| New antifungal antibiotics, benanomicins A and B inhibit infection of T-cell with human immunodeficiency virus (HIV) and syncytium formation by HIV. | H. Hoshino; J. Seki; T. Takeuchi | J. Antibiotics | 1989 | 42 | 344-346 |
| Biosynthesis of benanomicins. | S. Gomi; M. Sezaki; M. Hamada; S. Kondo; T. Takeuchi | J. Antibiotics | 1989 | 42 | 1145-1150 |
| Isolation of new minor benanomicins. | S. Kondo; S. Gomi; K. Uotani; S. Inouye; T. Takeuchi | J. Antibiotics | 1991 | 44 | 123-129 |
| Antifungal and antiviral activities of benanomicins and their analogues. | S. Kondo; S. Gomi; D. Ikeda; M. Hamada; T. Takeuchi; H. Iwai; J. Seki; H. Hoshino | J. Antibiotics | 1991 | 44 | 1228-1236 |
| A novel antifungal antibiotic, benanomicin A. | H. Yamaguchi; S. Inouye; Y. Orikasa; H. Tohyama; K. Komuro; S. Gomi; S. Ohuchi; T. Matsumoto; M. Yamaguchi; T. Hiratani; K. Uchida; Y. Ohsumi; S. Kondo; T. Takeuchi | Recent Progress in Antifungal Chemotherapy (Eds. H. Yamaguchi; G. S. Kobayashi; H. Takahashi)Marcel Dekker, Inc., New York/Basel/Hong Kong | 1991 | 393-402 | |
| Amino acid analogs of benanomicin A through desalaninebenanomicin A. | D. Ikeda; T. Nishizuka; S-P. Huang; S. Kondo; T. Takeuchi | J. Antibiotics | 1992 | 45 | 1645-1652 |
| New hydroxybenanomicins produced by actinomadura. | S. Kondo; S. Gomi; K. Uotani; S. Miyakawa; S. Inouye; D. Ikeda; T. Takeuchi | Drugs Exptl. Clin. Res. | 1992 | 18 | 217-224 |
| Identification of strain MH193-16F4, a benanomicin-producing actinomycete, to Actinomadura spadix. | N. Kinoshita; M. Okada; M. Hamada | Actinomycetologica | 1994 | 8 | 73-78 |
| Successful treatment of Pneumocystis carinii pneumonia in mice with benanomicin A (ME1451). | A. Yasuoka; S. Oka; K. Komuro; H. Shimizu; K. Kitada; Y. Nakamura; S. Shibahara; T. Takeuchi; S. Kondo; K. Shimada; S. Kimura | Antimicorbial Agents and Chemotherapy | 1995 | 39 | 720-724 |
| Binding of benanomicin A to fungal cells in reference to its fungicidal action. | M. Watanabe; S. Gomi; H. Tohyama; K. Ohtsuka; S. Shibahara; S. Inouye; H. Kobayashi; S. Suzuki; S. Kondo; T. Takeuchi; H. Yamaguchi | J. Antibiotics | 1996 | 49 | 366-373 |
| Antifungal antibiotic benanomicin A increases susceptibility of Candida albicans to phagocytosis by murine macrophages. | H. Watabe; T. Mikuniya; S. Inouye; S. Abe; H. Yamaguchi; S. Kondo; T. Takeuchi; T. W. Klein; H. Friedman; Y. Yamamoto | J. Antibiotics | 1996 | 49 | 1221-1225 |
| The in-vitro activity of an antifungal antibiotic benanomicin A in comparison with amphotericin B. | M. Watanabe; T. Hiratani; K. Uchida; K. Ohtsuka; H. Watabe; S. Inouye; S. Kondo; T. Takeuchi; H. Yamaguchi | J. Antimicrobial Chemother. | 1996 | 38 | 1073-1077 |
| A synthetic approach to benanomicin A: Synthesis of the substituted 5,6-dihydrobenzo[a]naphthacenequinone. | S. Hirosawa; T. Nishizuka; S. Kondo; D. Ikeda | Chemistry Letters | 1997 | 26 | 305-306 |
| Synthesis of optically active α-tetralone: A key intermediate to natural benanomicinone. | T. Nishizuka; S. Hirosawa; M. Tsushima; S. Kondo; D. Ikeda | Chemistry Letters | 1997 | 26 | 543-544 |
| A synthetic approach to benanomicin A 1. Synthesis of 5,6-dihydrobenzo[a]naphthacenequinone. | S. Hirosawa; T. Nishizuka; S. Kondo; D. Ikeda; T. Takeuchi | J. Antibiotics | 1997 | 50 | 685-689 |
| A synthetic approach to benanomicin A. 2. Synthesis of the substituted 5,6-dihydrobenzo[a]naphthacenequinone. | T. Nishizuka; S. Hirosawa; S. Kondo; D. Ikeda; T. Takeuchi | J. Antibiotics | 1997 | 50 | 755-764 |
| Selective deoxygenation and O-methylation of benanomicin A: Synthesis of 9-deoxy-, 9-O-methyl- and 14-O-methylbenanomicin A. | T. Nishizuka; S. Hirosawa; M. Hamada; S. Kondo; D. Ikeda; T. Takeuchi | J. Antibiotics | 1997 | 50 | 765-769 |
| The in-vivo activity of an antifungal antibiotic, benanomicin A, in comparison with amphotericin B and fluconazole. | K. Ohtsuka; M. Watanabe; Y. Orikasa; S. Inouye; K. Uchida; H. Yamaguchi; S. Kondo; T. Takeuchi | J. Antimicrobial Chemotherapy | 1997 | 39 | 71-77 |
| Mode of antifungal action of benanomicin A in Saccharomyces cerevisiae. | M. Watanabe; H. Tohyama; T. Hiratani; H. Watabe; S. Inouye; S. Kondo; T. Takeuchi; H. Yamaguchi | J. Antibiotics | 1997 | 50 | 1042-1051 |
| Morphological alterations of Saccharomyces cerevisiae induced by benanomicin A, an antifungal antibiotic with mannan affinity. | M. Watanabe; Y. Nishiyama; S. Inouye; H. Yamaguchi; S. Kondo; T. Takeuchi | Microbiol. Immunol. | 1998 | 42 | 365-370 |