Compounds

Heliquinomycin

Heliquinomycin_1

Producing organism:

Streptomyces sp. MJ929-SF2

Activity:

DNA helicase inhibitor

Clinical use:

-

Class no:

4 Reference(s)

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Title Author Journal Year Volume Page
Heliquinomycin, a new inhibitor of DNA helicase, produced by Streptomyces sp. MJ929-SF2 I. Taxonomy, production, isolation, physico-chemical properties and biological activities. M. Chino; K. Nishikawa; M. Umekita; C. Hayashi; T. Yamazaki; T. Tsuchida; T. Sawa; M. Hamada; T. Takeuchi J. Antibiotics 1996 49 752-757
Heliquinomycin, a new inhibitor of DNA helicase, produced by Streptomyces sp. MJ929-SF2 II. Structure determination of heliquinomycin. M. Chino; K. Nishikawa; T. Tsuchida; R. Sawa; H. Nakamura; K. S. Nakamura; Y. Muraoka; D. Ikeda; H. Naganawa; T. Sawa; T. Takeuchi J. Antibiotics 1997 50 143-146
Heliquinomycin, a new inhibitor of DNA helicase, produced by Streptomyces sp. MJ929-SF2. III. Biosynthesis. M. Chino; K. Nishikawa; R. Sawa; M. Hamada; H. Naganawa; T. Sawa; T. Takeuchi J. Antibiotics 1997 50 781-784
Effect of a novel antibiotic, heliquinomycin, on DNA helicase and cell growth. M. Chino; K. Nishikawa; A. Yamada; M. Ohsono; T. Sawa; F. Hanaoka; M. Ishizuka; T. Takeuchi J. Antibiotics 1998 51 480-486