Compounds

Amastatin

Amastatin_1

Producing organism:

Streptomyces sp.

Activity:

Aminopeptidase A inhibitor

Clinical use:

-

Class no:

5 Reference(s)

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Title	Author	Journal	Year	Volume	Page
Amastatin, an inhibitor of aminopeptidase A, produced by Actinomycetes.	T. Aoyagi; H. Tobe; F. Kojima; M. Hamada; T. Takeuchi; H. Umezawa	J. Antibiotics	1978	31	636-638
Structure and chemical synthesis of amastatin.	H. Tobe; H. Morishima; H. Naganawa; T. Takita; T. Aoyagi; H. Umezawa	Agric. Biol. Chem.	1979	43	591-596
Purification by affinity chromatography using amastatin and properties of aminopeptidase A from pig kidney.	H. Tobe; F. Kojima; T. Aoyagi; H. Umezawa	Biochim. Biophys. Acta	1980	613	459-468
Synthesis and structure-activity relationships of amastatin analogues, inhibitors of aminopeptidase A.	H. Tobe; H. Morishima; T. Aoyagi; H. Umezawa; K. Isshiki; K. Nakamura; T. Yoshioka; Y. Shimauchi; T. Inui	Agric. Biol. Chem.	1982	46	1865-1872
Mitogenic potentials of bestatin, amastatin, arphamenines A and B, FK-156 and FK-565 on spleen lymphocytes.	N. Weissmann; G. Leyhausen; A. Maidhof; W. Tanaka; H. Umezawa; W. E. G. Mueller	J. Antibiotics	1985	38	772-778