Biology DivisionLaboratory of Microbial Carcinogenesis
Masanori HATAKEYAMA, M.D., Ph.D.
Laboratory Head, Laboratory of Microbial Carcinogenesis, Institute of Microbial Chemistry
Numazu Branch Head, Institute of Microbial Chemistry
Project Professor, Institute for Genetic Medicine, Hokkaido University (Concurrent appointment)
Professor Emeritus, The University of Tokyo
Favorites
- Classic rock music（60-70's rock）
- Classic Rakugo（especially, Master Bunji KATSURA）
- Old temples, downtown, and skyscrapers
Biography
- 1981
- School of Meidicine, Hokkaido University, Sapporo, Japan (M.D.)
- 1985
- Graduate School of Medicine, Hokkaido University, Sapporo Japan (Ph.D.)
- 1986-1991
- Assistant Professor, Institute for Molecular and Cellular Biology, Osaka University, Osaka, Japan
- 1991-1994
- Postdoctoral Fellow, Whitehead Institute, Massachusetts Institute of Technology (MIT), Cambridge, USA
- 1995-1999
- Member and Chief, Department of Viral Oncology, The Cancer Institute, Japanese Foundation for Cancer Research (JFCR), Tokyo, Japan
- 1999-2009
- Professor, Division of Molecular Oncology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan
- 2009-2022
- Professor, Division of Microbiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (June 2022: Professor Emeritus, The University of Tokyo)
- 2015-2020
- Vice Director, Max-Planck / The University of Tokyo Center for Integrative Inflammology
- 2022-present
- Laboratory Head, Laboratory of Microbial Oncology, Institute of Microbial Chemistry, Microbial Chemistry Research Froundation (MCRF), Tokyo, Japan
- 2022-present
- Branch Head, Institute of Microbial Chemistry, Numazu, Microbial Chemistry Research Foundation (MCRF), Numazu, Japan
- 2022-present
- Project Professor, Center for Infection-Associated Cancer, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan
- 1991
- Incitment Award of the Japanese Cancer Association
- 1991
- Human Frontier Science Program (HFSP) Long-term Fellowship
- 2006
- JCA-Mauvernay Award
- 2011
- Sagawa Special Award
- 2014
- Medical Award of the Japan Medical Association
- 2016
- Hideyo Noguchi Memorial Medical Prize
- 2019
- The Medal of Honor with Purple Ribbon
- 2019
- The Tomizo Yoshida Award of the Japanese Cancer Association
- 2022
- Princess Takamatsu Cancer Research Fund Prize
- 2022
- The Takeda Prize for Medical Science
Educations
Academic Positions
Honors
Publications
- Hatakeyama,M., Minamoto, S., Uchiyama, T., Hardy, R.R., Yamada, G. and Taniguchi, T. (1985) Reconstitution of functional receptor for human interleukin-2 in mouse cells. Nature, 318, 467-470.
- Hatakeyama, M., Minamoto, S. and Taniguchi, T. (1986) Intracytoplasmic phosphorylation sites of Tac antigen(p55) are not essential for the conformation, function, and regulation of human interleukin-2 receptor. Proc. Natl. Acad. Sci. USA, 83, 9650-9654.
- Hatakeyama, M., Tsudo, M., Minamoto, S., Kono, T., Doi, T., Miyata, T., Miyasaka, M. and Taniguchi, T. (1989) Interleukin-2 receptor b chain gene: Generation of three receptor forms by cloned human a and b chain cDNA's. Science, 244, 551-556.
- Hatakeyama, M., Mori, H., Doi, T. and Taniguchi, T. (1989) A restricted cytoplasmic region of IL-2 receptor b chain is essential for growth signal transduction, but not for ligand binding and internalization. Cell, 59, 837-845.
- Hatakeyama, M., Kono, T., Kobayashi, N., Kawahara, A., Levin, S.D., Perlmutter, R.M. and Taniguchi, T. (1991) Interaction of the IL-2 receptor with the src-family kinase p56lck: Identification of novel intermolecular interaction. Science, 252, 1523-1528.
- Hatakeyama, M., Kawahara, A., Mori, H., Shibuya, H. and Taniguchi, T. (1992) c-fos gene induction by interleukin 2: Identification of the critical cytoplasmic regions within the interleukin 2 receptor b chain. Proc. Natl. Acad. Sci. USA, 89, 2022-2026.
- Hatakeyama, M., Brill, J., Fink, G.R. and Weinberg, R.A. (1994) Collaboration of G1 cyclins in the functional inactivation of the retinoblastoma protein. Genes Dev., 8, 1759-1771.
- Hatakeyama, M., Herrera, R.A., Makela, T., Dowdy, S.F., Jacks, T. and Weinberg, R.A. (1995) The Cancer cell and the cell cycle. Cold Spring Harbor Symposia on Quantitative Biology, 59, 1-10.
- Hatakeyama, M. and Weinberg, R.A. (1996) The role of RB in cell cycle control. Progress Cell Cycle Res., 1, 9-19.
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