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Title Authors Journal Year Vol Pages
A defucosylated anti-EpCAM monoclonal antibody (EpMab-37-mG2a-f) exerts antitumor activity in xenograft model. T. Asano, T. Tanaka, H. Suzuki, G. Li, T. Ohishi, M. Kawada, T. Yoshikawa, M. K. Kaneko, and Y. Kato Antibodies 2022 11 74. https://doi.org/10.3390/antib11040074
Defucosylated mouse-dog chimeric anti-HER2 monoclonal antibody (H77Bf) exerts antitumor activities in mouse xenograft models of canine osteosarcoma. R. Nanamiya, T. Ohishi, H. Suzuki, T. Mizuno, T. Yoshikawa, T. Asano, T. Tanaka, M. K. Kaneko, and Y. Kato Monoclon. Antib. Immunodiagn. Immunother. 2022 doi:10.1089/mab.2022.0022
Antitumor activity of an anti-EGFR/HER2 bispecific antibody in a mouse xenograft model of canine osteosarcoma. N. Tateyama, H. Suzuki, T. Ohishi, T. Asano, T. Tanaka, T. Mizuno, T. Yoshikawa, M. Kawada, M. K. Kaneko, and Y. Kato Pharmaceutics 2022 14 2494, https://doi.org/10.3390/pharmaceutics14112494
Antitumor activities in mouse xenograft models of canine fibroblastic tumor by defucosylated mouse-dog chimeric anti-HER2 monoclonal antibody (H77Bf). H. Suzuki, T. Asano, T. Ohishi, T. Yoshikawa, H. Suzuki, T. Mizuno, T. Tanaka, M. Kawada, M. K. Kaneko, and Y. Kato Monoclon. Antib. Immunodiagn. Immunother. 2022 doi: 10.1089/mab.2022.0023
Antisense gapmers with LNA-wings and (S)-5′-C-aminopropyl-2-arabinofluoro-nucleosides could efficiently suppress the expression of KNTC2.
Y. Zhou, S. Sakamoto and Y. Ueno Molecules 2022 27 7384. doi: 10.3390/molecules27217384
A missing link in multisubstituted pyrrolidines: remote stereocontrol forged by rhodium-alkyl nitrene. X. Tang, R. K. Tak, H. Noda, and M. Shibasaki Angew. Chem. Int. Ed. 2022 61 doi: 10.1002/anie.202212421.
Targeting the ATG5-ATG16L1 protein-protein interaction with a hydrocarbon-stapled peptide derived from ATG16L1 for autophagy inhibition. J. Cui, Y. Ogasawara, I. Kurata, K. Matoba, Y. Fujioka, N. N. Noda, M. Shibasaki, and T. Watanabe J. Am. Chem. Soc. 2022 144 doi: 10.1021/jacs.2c07648
Anti‑lung cancer properties of cyanobacterial bioactive compounds. M. S. Baig, S. Rajpoot, T. Ohishi, R. Savai, S. Seidel, N. A. Kamennaya, E. E. Bezsonov, A. N. Orekhov, P. Mahajan, K. Solanki, and U. Saqib Archives of Microbiology 2022 204 603, https://doi.org/10.1007/s00203-022-03194-0
Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer. Y. Kubota, Y. Fujioka, A. Patil, Y. Takagi, D. Matsubara, M. Iijima, I. Momose, R. Naka, K. Nakai, N. N. Noda, and M. Takekawa Nat. Commun. 2022 13 4063. doi: 10.1038/s41467-022-31690-w.
Structural analysis of spike proteins from SARS-CoV-2 variants of concern highlighting their functional alterations. K. Solanki, S. Rajpoot, A. Kumar, K. Y J Zhang, T. Ohishi, N. Hirani, K. Wadhonkar, P. Patidar, Q. Pan, and M. S Baig Future Virol. 2022 Jul; 10.2217/fvl-2022-0003. doi: 10.2217/fvl-2022-0003.
Short peptides derived from hGAPDH exhibit anti-cancer activity. J. Yoshida, K. Takayama, and M. Kawada Bioorganic & Medicinal Chemistry 2022 71 116953. doi.org/10.1016/j.bmc.2022.116953
Defucosylated mouse‑dog chimeric anti‑HER2 monoclonal antibody exerts antitumor activities in mouse xenograft models of canine tumors. H. Suzuki, T. Ohishi, T. Asano, T. Tanaka, M. Saito, T. Mizuno, T. Yoshikawa, M. Kawada, M. K. Kaneko, and Y. Kato Oncol. Rep. 2022 48 154. doi: 10.3892/or.2022.8366
Epigallocatechin gallate (EGCG) attenuates severe acute respiratory coronavirus disease 2 (SARS-CoV-2) infection by blocking the interaction of SARS-CoV-2 spike protein receptor-binding domain to human angiotensin-converting enzyme 2. T. Ohishi, T. Hishiki, M. S. Baig, S. Rajpoot, U. Saquib, T. Takasaki, and Y. Hara PLoS One 2022 17 e0271112. doi: 10.1371/journal.pone.0271112
Anti-cancer effects of dietary polyphenols via ROS-mediated pathway with their modulation of microRNAs. Y. Yoshioka, T. Ohishi, Y. Nakamura, R. Fukutomi and N. Miyoshi Molecules 2022 27 3816. doi.org/10.3390/molecules27123816
Defucosylated anti-EGFR monoclonal antibody exerted antitumor activities in mouse xenograft models of canine mammary gland tumor.
T. Tanaka, T, Ohishi, M. Saito, H. Suzuki, M. K. Kaneko, M. Kawada, and Y. Kato Monoclonal Antibodies in Immunodiagnosis and Immunuotherapy
2022 41 142-149. doi: 10. 1089/mab. 2022. 0009
A novel E198K substitution in the PA gene of influenza A virus with reduced susceptibility to baloxavir acid. N. Takizawa and F. Momose
Arch. Virol.
2022 167 1565-1570 (doi: 10.1007/s00705-022-05456-0)
Diastereoselective direct catalytic asymmetric Mannich-type reactions of alkylnitriles with a Ni(II)-carbene complex. S. Adachi, A. Saito, and M. Shibasaki Org. Lett. 2022 24 3901-3906. doi.org/10.1021/acs.orglett.2c01624
A defucosylated mouse anti-CD10 monoclonal antibody (31-mG2a-f) exerts antitumor activity in a mouse xenograft model of renal cell cancers. H. Kawabata, T. Ohishi, H. Suzuki, T. Asano, M. Kawada, H. Suzuki, M. K. Kaneko and Y. Kato Monoclon Antib Immunodiagn Immunother. 2022 doi. org/10. 1089/mab. 2021. 0049. PMID: 35483055
Concise and stereodivergent approach to chromanone lactones through copper-catalyzed asymmetric vinylogous addition of siloxyfurans to 2-ester-substituted chromones. J. Cui, R. Oriez, H. Noda, T. Watanabe and M. Shibasaki Angew. Chem. Int. Ed. 2022 61 e202203128 (doi. org/10. 1002/anie. 202203128)
A defucosylated mouse anti-CD10 monoclonal antibody (31-mG2a-f) exerts antitumor activity in a mouse xenograft model of CD10-overexpressed tumors. H. Kawabata, H. Suzuki, T. Ohishi, M. kawada, M. K. Kaneko and Y. Kato Monoclon Antib Immunodiagn Immunother. 2022 41 59-66. doi: 10.1089/mab. 2021. 0048. PMID: 35471051
Antitumor activities in mouse xenograft models of canine mammary gland tumor by defucosylated mouse-dog chimeric anti-EGFR antibody (E134Bf). G. Li, H. Suzuki, J. Takei, T. Asano, M. Sano, T. Tanaka, H. Harada, T. Mizuno, T. Ohishi, M. Kawada, M. K. Kaneko and Y. Kato Monoclon Antib Immunodiagn Immunother. 2022 41 53-58. doi: 10.1089/mab. 2021. 0040. PMID: 35471048
Synthesis, gene silencing activity, thermal stability, and serum stability of siRNA containing four (S)-5’-C-aminopropyl-2’-O-methylnucleosides (A, adenosine; U, uridine; G, guanosine; and C, cytidine). R. Kajino, S. Sakamoto and Y. Ueno RSC Advances 2022 12 11454. doi.org/10.1039/D2RA00705C
Antitumor activities in mouse xenograft models of canine fibroblastic tumor by defucosylated anti-EGFR monoclonal antibody. N. Goto, H. Suzuki, T. Ohishi, A. Harakawa, G. Li, M. Saito, J. Takei, T. Tanaka, T. Asano, M. Sano, M. Kawada, M. Kaneko, and Y. Kato Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 2022 42 doi: 10.1089/mab.2021.0059
Synthesis and antiviral activity of formycin derivatives with anti-influenza virus activity. H. Takada, N. Takizawa, S. Shibasaki, H. Asaba, M. Igarashi, M. Shibasaki and Y. Takahashi Bioorganic & Medicinal Chemistry 2022 57 https://doi.org/10.1016/j.bmc.2022.116613
Rediscovery of 4-trehalosamine as a biologically stable, mass-producible, and chemically modifiable trehalose analog. S. Wada, H. Arimura, M. Nagayoshi, R. Sawa, Y. Kubota, K. Matoba, C. Hayashi, Y. Shibuya, M. Hatano, Y. Takehana, S. Ohba, Y. Kobayashi, T. Watanabe, M. Shibasaki, and M. Igarashi Advanced Biology 2022 6 https://doi.org/10.1002/adbi. 202101309
Involvement of microRNA modifications in anticancer effects of major polyphenols from green tea, coffee, wine, and curry. T. Ohishi, S. Hayakawa and N. Miyoshi Critical Reviews in Food Science and Nutrition 2022 62 https://doi.org/10.1080/10408398. 2022. 2038540
TrMab-6 exerts antitumor activity in mouse xenograft models of breast cancers.  T. Tanaka, T. Ohishi, M. Saito, M. Kawada, M. K. Kaneko and Y. Kato Monoclon Antib Immunodiagn Immunother. 2022 41 32-38. doi:10.1089/mab.2021.0056. PMID: 35225665 
Defucosylated anti-EGFR monoclonal antibody (134-mG2a-f) exerts antitumor activities in mouse xenograft models of canine osteosarcoma. R. Nanamiya, J. Takei, T. Ohishi, T. Asano, T. Tanaka, M. Sano, T. Nakamura, M. Yanaka, S. Handa, Y. Komatsu, H. Hosono, N. Tateyama, Y. Harigae, M. Saito, H. Suzuki, M. Kawada, M. K. Kaneko and Y. Kato Monoclon Antib Immunodiagn Immunother. 2022 41 1-7. doi: 10.1089/mab.2021.0036. PMID: 35225663
Anti-influenza virus activity of methylthio-formycin distinct from that of T-705.

N. Takizawa, H. Takada, M. Umekita, M. Igarashi and Y. Takahashi Front Microbiol. 2022 13 802671. doi:10.3389/fmicb.2022.802671
Update and nomenclature proposal for mammalian lysophospholipid acyltransferases which create membrane phospholipid diversity. W. J. Valentine, K. Yanagida, H. Kawana, N. Kono, N. N. Noda, J. Aoki and H. Shindou. J. Biol. Chem. 2022 298 101470. doi: 10.1016/j.jbc.2021.101470
Polyether ionophore kijimicin inhibits growth of Toxoplasma gondii and controls acute toxoplasmosis in mice. A. Leesombun, CI. Nihei, D. Kondoh and Y. Nishikawa Parasitol. Res. 2022 121 413-422. doi: 10.1007/s00436-021-07363-w. 
Isolation of new derivatives of the 20-membered macrodiolide bispolide from Kitasatospora sp. MG372-hF19. Y. Kohda, S. Sakamoto, M. Umekita,, T. Kimura, Y. Kubota, R. Arisaka, Y. Shibuya, H. Muramatsu, R. Sawa, S. Dan, M. Kawada and M. Igarashi J. Antibiot. 2022 75 77-85. doi.org/10.1038/s41429-021-00492-5