Ln-BINOL-Ph3As=O System

> Catalytic Asymmetric Epoxidation
> Expansion to Polyol Synthesis
> Expansion to Various Tandem Process

Review:
J. Synth. Org. Chem., Jpn. 2002, 60, 94-105.
Catalytic Asymmetric Epoxidation
α,β-unsaturated ketone



Nemoto,T.; Ohshima, T.; Yamaguchi, K.; Shibasaki, M. J. Am. Chem. Soc. 2001, 123, 2725-2732.

α,β-unsaturated imdazolide


Nemoto, T.; Ohsima, T.; Shibasaki, M. J. Am. Chem. Soc. 2001, 123, 9474-9475.
Nemoto, T.; Tosaki, S.-y.; Ohsima, T.; Shibasaki, M. Chirality 2003, 15, 306-311.

α,β-unsaturated amide



Nemoto, T.; Kakei, H.; Gnanadesikan, V.; Tosaki, S.; Ohsima, T.; Shibasaki, M. J. Am. Chem. Soc. 2002, 124, 14544-14545.

α,β-unsaturated N-Acylpyrrole


Kinoshita, T..; Okada, S.; Park, S. R.; Matsunaga, S; Shibasaki, M. Angew. Chem. Int. Ed. 2003, 42, 4680-4684.
Matsunaga,S.; Kinoshita, T.; Okada, S.; Harada, S.; Shibasaki, M. J. Am. Chem. Soc. 2004, 126, 7559-7570.

α,β-unsaturated ester



Kakei, H.; Tsuji, R.; Ohsima, T.; Shibasaki, M. J. Am. Chem. Soc. 2005, 127, 8962-8963.
Expansion to Polyol Synthesis




Tosaki, S.-y.; Horiuchi, Y.; Nemoto, T.; Ohshima, T.; Shibasaki, M. Chem. Eur. J. 2004, 10, 1527-1544.

Expansion to Various Tandem Process




Tosaki, S.-y.; Tsuji, R.; Ohsima, T.; Shibasaki, M. J. Am. Chem. Soc. 2005, 127, 2147-2155.

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